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Satyr
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PostSubject: EpiGenetics EpiGenetics EmptyWed Aug 01, 2012 10:59 am



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Lyssa
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PostSubject: Re: EpiGenetics EpiGenetics EmptyWed Aug 01, 2012 6:42 pm

What a nice find; so fascinating, thank you.

It redeems how not just the end result and getting the job done matters, but 'how' you get the job done...
It redeems Philosophy as an art of 'how'... more than a toward-what and where-to.
It redeems a Karmic perspective.

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"ἐδιζησάμην ἐμεωυτόν." [Heraclitus]

"All that exists is just and unjust and equally justified in both." [Aeschylus, Prometheus]

"The history of everyday is constituted by our habits. ... How have you lived today?" [N.]

*Become clean, my friends.*
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Satyr
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PostSubject: Re: EpiGenetics EpiGenetics EmptyWed Aug 01, 2012 7:34 pm

It supports the idea that man is the sum of all his past.

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PostSubject: Re: EpiGenetics EpiGenetics EmptyWed Aug 01, 2012 9:34 pm

What I find interesting is how they mentioned when epigenetics can actually be affected and how it is different for male and female. I recall them saying that females have theirs affected only in the womb and males have it all the way up until puberty.
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PostSubject: Re: EpiGenetics EpiGenetics EmptySun Nov 18, 2012 10:14 pm

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The comments section brings up some great questions and some bile from one "Ted," who nails the hypocrisy of a lot of White red-meat types who are disdainful of intellectualism and science, or only invoke scientific research when it suits their purposes, as if it were a magic spell or spiritual entity.

...Which, Julian Jaynes would say, is precisely what "Science" is these days.
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PostSubject: Re: EpiGenetics EpiGenetics EmptyWed Nov 28, 2012 2:58 pm

Jaynes and Pinker.

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PostSubject: Re: EpiGenetics EpiGenetics EmptySat Dec 22, 2012 1:20 am

Epigenetics May Be a Critical Factor Contributing to Homosexuality, Study Suggests
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Quote :
Epigenetics -- how gene expression is regulated by temporary switches, called epi-marks -- appears to be a critical and overlooked factor contributing to the long-standing puzzle of why homosexuality occurs.

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PostSubject: Re: EpiGenetics EpiGenetics EmptySat Dec 22, 2012 9:45 am

I love this whole scene of "Lord of the Ring - Fellowship of the Ring" between Aragorn and Arwen, but for this topic I specifically mean the sequence from 0:00 until 1min:

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PostSubject: Re: EpiGenetics EpiGenetics EmptySat Dec 22, 2012 10:26 am

Now that is a good movie. One of the few modern ones that retains a sense of nobility and heroism.

“All that is gold does not glitter,
Not all those who wander are lost;
The old that is strong does not wither,
Deep roots are not reached by the frost.

From the ashes a fire shall be woken,
A light from the shadows shall spring;
Renewed shall be blade that was broken,
The crownless again shall be king.”

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PostSubject: Re: EpiGenetics EpiGenetics EmptyWed Aug 21, 2013 9:13 am


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"ἐδιζησάμην ἐμεωυτόν." [Heraclitus]

"All that exists is just and unjust and equally justified in both." [Aeschylus, Prometheus]

"The history of everyday is constituted by our habits. ... How have you lived today?" [N.]

*Become clean, my friends.*
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Lyssa
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PostSubject: Re: EpiGenetics EpiGenetics EmptyWed Jan 22, 2014 10:58 am

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-

Some people are paid to do technical writings for a job, and designing ready-made love-letters or doing write-ups on love-stores, crafting erotic letters, etc. is one of them; a typical sample from the internet...

"You Will Always Be In My Heart
by Tanya
Dear Rodney,

I could kiss you a thousand times and still not be satisfied. My love for you is endless, so tender, so hot and complete. I swear to God I want you in my life. I love you more and more with each day passing and it eases me to know as tomorrow approaches, that I will love you more then yesterday and tomorrow will be more then today. My love for you cannot be measured by words alone as love does express my true feelings for you.

When I think of our love it reminds me of all the things you are to me. You and only you have given me so much hope and have made me realize how much I want you! You show the true meaning of how a man should treat a woman.

Rodney, please accept my heart as your own and listen to both of ours beating as one. You are my reason to live. Without you I'm nothing. The years will be a test, but nothing will keep me from loving you, or from being by your side. I love you more than you could even know, you are my world. I just wanted to let you know how much I love all that you are and will be. You're truly my love, my soul mate, and my best friend.

For the first time in my life I have something to believe in. You've seen me at my worst and still take me as I am. I thank God for you every day because I know you're heaven sent, you are my angel. I love you from now till death do us part.

Right now you live far away from me and I really mean it's killing me but I know in my heart that we are doing alright. I don't want to lose you to anyone else or anything that anyone wants to say about you. I want you to know I love you from the deepest part of my heart. I'm always so lost for words when it comes to you, I just wish there was another way that we could be together.

I want you and always will and there is nothing that will ever change the way I feel about you ... I love you! Love can make you do things that you never thought possible. See, there's a place in me where your fingerprints still rest, your kisses still linger and your whispers softly echo. It's the place where a part of you will forever be a part me. I promise, you'll always be in my heart. I love you.

Love always,

Tanya"

-

Yesterday, even more after the exchanges and behaviours of those like FC, etc., I had the thought all the gestures and traits and trains of thought you pick up in your oldest age, like even when you are 90 - may actually show up if ever your greatgreat grandchild came into this world. So, learning can never end and so... Nobility has to be a lifepath till the very end.

Tailor-made love-letters and framing heroic ontologies for word-play and everything that is not authentically experienced, that does not arise or become a part of your body and being, and merely remain tools to appear socially effective or garner temporary success is a part of you that will forever be lost to entropy.
Knowing Thyself - what doesn't authentically arise from every part of your being and not just your mental consciousness [anyone can quote a shakespeare poem from memory], is a part of you that will not live on Epigenetically even if one does live on genetically into the future.
Traits, gestures, thought-Modes, approaches even when you are in your death-bed need not come to perfect consciousness but be lived out authentically as an inner experience creating a subtle memory, a code that gets passed on, with the chances of showing up in some generation far into the future when one may not even be alive to see these effects.

Those like FC who believe lesbianism is cool as long as it does not make for a sore sight... and then go on to create Noble philosophical systems - cannot but be wasting their lives. There are those who want to "get by" life, just surviving the present with cleverness. But a genetic triumph does not automatically imply an epigenetic triumph...
Nobility, Heroism, "Love" cannot be faked in the larger ecology of life, which are either paths of life or they are not - very black and white. Anyone who thinks otherwise, parroting heroic words and thoughts but "living" out dishonestly is literally a loser.

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"ἐδιζησάμην ἐμεωυτόν." [Heraclitus]

"All that exists is just and unjust and equally justified in both." [Aeschylus, Prometheus]

"The history of everyday is constituted by our habits. ... How have you lived today?" [N.]

*Become clean, my friends.*


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Satyr
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PostSubject: Re: EpiGenetics EpiGenetics EmptyWed Jan 22, 2014 11:08 am

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The need to be included in the group can be stressful. To be excluded can be a life-threatening possibility.

The desire to agree with whatever is popular, or satisfies this all-inclusive, which would guarantee your own inclusion, must overwhelm even the brightest of minds.
We all know of the pressures placed upon those rare intellectuals who dare to speak of politically-incorrect subjects in very public and honest ways. We know what threats they receive what pressures are placed upon them as individuals...and this is why we admire such people.

The common man would never dare.
If someone can convince himself that sex did not evolve to replicate genes then you can be certain that none of his judgements will veer outside the cultural norms, and nothing you tell him will come close to convincing him that he might be absurd to the point of retardation.

The brain is a survival tool, and if it feels threatened by a possibility then it will ensure that its own survival takes precedence over any other consideration...such as clarity, honesty, and so on.
If lying to one's self or to the other will protect it from what it considers a life-threatening position then it will do whatever it must to preserve itself.

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PostSubject: Re: EpiGenetics EpiGenetics EmptySun Feb 09, 2014 12:26 pm

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"ἐδιζησάμην ἐμεωυτόν." [Heraclitus]

"All that exists is just and unjust and equally justified in both." [Aeschylus, Prometheus]

"The history of everyday is constituted by our habits. ... How have you lived today?" [N.]

*Become clean, my friends.*
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Satyr
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PostSubject: Re: EpiGenetics EpiGenetics EmptyMon Feb 10, 2014 7:39 pm

I wonder if anyone remembers a study - I think it was conducted by the Swedes - about how genes are being updated up until the moment of fertilization. I guess the male sperm is continuously being updated with new data and carries the male's experiences with environment up until the moment the spermatozoa are produced.
I recall seeing it but lost it in time.

I wonder if this also applies to female ovum because that is created early on in a female's sexual life cycle.
Perhaps the male's contribution is more decisive than we may have thought.

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PostSubject: Re: EpiGenetics EpiGenetics EmptyTue Feb 11, 2014 1:23 am

Satyr wrote:
I wonder if anyone remembers a study - I think it was conducted by the Swedes - about how genes are being updated up until the moment of fertilization. I guess the male sperm is continuously being updated with new data and carries the male's experiences with environment up until the moment the spermatozoa are produced.
I recall seeing it but lost it in time.

I wonder if this also applies to female ovum because that is created early on in a female's sexual life cycle.
Perhaps the male's contribution is more decisive than we may have thought.
 

Wasn't that already covered by the Ghost in your Genes documentary based on the Swedes (overkalix village and the famine study); is there another one?

Quote :
"Longevity determined by paternal ancestors' nutrition during their slow growth period.
Bygren LO, Kaati G, Edvinsson S.

Abstract
Social circumstances often impinge on later generations in a socio-economic manner, giving children an uneven start in life. Overfeeding and overeating might not be an exception. The pathways might be complex but one direct mechanism could be genomic imprinting and loss of imprinting. An intergenerational "feedforward" control loop has been proposed, that links grandparental nutrition with the grandchild's growth. The mechanism has been speculated to be a specific response, e.g. to their nutritional state, directly modifying the setting of the gametic imprint on one or more genes. This study raises the question: Can overnutrition during a child's slow growth period trigger such direct mechanisms and partly determine mortality? Data were collected by following-up a cohort born in 1905 in Overkalix parish, northernmost Sweden. The probands were characterised by their parents' or grandparents' access to food during their own slow growth period. Availability of food in the area was defined by referring to historical data on harvests and food prices, records of local community meetings and general historical facts. If there was a surfeit of food in the environment when the paternal grandfather was a 9-12 year old boy a shortening of the proband survival could be demonstrated. The influence of parents', maternal grandparents' and paternal grandmothers' access to food during their slow growth period was discounted in a multivariable analysis. The results are indicative of very early programming mechanisms in human adaptation to the social environment."
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Quote :
"Maternal Epigenetic Transfer

Moms transfer epigenetic effects via two routes. First, as an epigenetic factor herself. After all, the mom is the primary environment for the fetus. Anything that happens to the mom – famine, stress, overnutrition, undernutrition, chronic sleep loss, terrorist attack – also happens to the fetus, sometimes even if it occurs pre-conception. Second, when a woman is pregnant, she’s not just carrying the fetus and transmitting epigenetic changes to the fetal genes from her life experiences. She also carries the fetus’ reproductive cells which will either develop into eggs or sperm. Any changes to the gene expression of these reproductive cells during their development in the fetus may also affect subsequent offspring. So at least three generations are affected by the environmental input during pregnancy: the mom, the fetus, and the fetus’ future offspring.

Paternal Epigenetic Transfer

Dads transfer epigenetic inheritance through changes to the sperm. If a male fetus is subjected to an epigenetic input in the womb as his reproductive cells are developing, he may grow up with forever altered sperm that in turn affects his progeny. As seen in the case of the Swedish village, male sperm may also be vulnerable in late childhood right before puberty, which is when sperm cells are maturing and “finalizing.” And then you’ve got the mouse studies that suggest inheritance can transfer even when the [You must be registered and logged in to see this link.]. The amount of research into paternal epigenetic transfer pales in comparison to that of maternal epigenetics, but it appears to play a role just the same (if perhaps not as prominent).

It’s easy to get bogged down in epigenetic mechanisms, but what you’re really here for is to learn how we can shape our offspring’s health. Let’s explore, shall we?

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"ἐδιζησάμην ἐμεωυτόν." [Heraclitus]

"All that exists is just and unjust and equally justified in both." [Aeschylus, Prometheus]

"The history of everyday is constituted by our habits. ... How have you lived today?" [N.]

*Become clean, my friends.*
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PostSubject: Re: EpiGenetics EpiGenetics EmptyTue Feb 11, 2014 1:25 am

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"ἐδιζησάμην ἐμεωυτόν." [Heraclitus]

"All that exists is just and unjust and equally justified in both." [Aeschylus, Prometheus]

"The history of everyday is constituted by our habits. ... How have you lived today?" [N.]

*Become clean, my friends.*
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Lyssa
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PostSubject: Re: EpiGenetics EpiGenetics EmptyTue Feb 11, 2014 2:24 am

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"ἐδιζησάμην ἐμεωυτόν." [Heraclitus]

"All that exists is just and unjust and equally justified in both." [Aeschylus, Prometheus]

"The history of everyday is constituted by our habits. ... How have you lived today?" [N.]

*Become clean, my friends.*
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PostSubject: Re: EpiGenetics EpiGenetics EmptyFri Jun 20, 2014 1:09 pm


_________________
1. "Youth, oh, youth! | of whom then, youth, art thou born?
Say whose son thou art,
Who in Fafnir's blood | thy bright blade reddened,
And struck thy sword to my heart."


2. "The Noble Hart | my name, and I go
A motherless man abroad;
Father I had not, | as others have,
And lonely ever I live."
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PostSubject: Re: EpiGenetics EpiGenetics EmptyFri Jun 20, 2014 1:22 pm

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Lyssa
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PostSubject: Re: EpiGenetics EpiGenetics EmptyTue Jul 15, 2014 8:55 pm

Quote :
"The not-so-subtle implication is that the reason one gets sick is because of one’s habits. Of course, there are a lot of lifestyle diseases, but the implications goes beyond the sensible, science-based observation that obesity and lack of exercise increase the risk of certain diseases, into the realm of stating that if you just eat the right foods and do the right exercises you’ll never get sick.

Utter nonsense, of course.


You can probably see why quacks have seized on epigenetics so eagerly. If there’s one thing quacks hate, it’s genetics. The reason, of course, is that they view genes simplistically in a deterministic fashion, constructing an elaborate straw man of modern genetics in which genes are destiny. Epigenetics frees them from that, because they can now use it as a near-magical talisman to invoke as an alleged mechanism by which one’s activities can permanently alter one’s gene expression. I just saw a doozy of an example yesterday on–where else?–Joe Mercola’s website. It’s an article entitled
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Mercola:

"The major problem with believing the myth that your genes control your life is that you become a victim of your heredity. Since you can’t change your genes, it essentially means that your life is predetermined, and therefore you have very little control over your health. With any luck, modern medicine will find the gene responsible and be able to alter it, or devise some other form of drug to modify your body’s chemistry, but aside from that, you’re out of luck… The new science, however, reveals that your perceptions control your biology, and this places you in the driver’s seat, because if you can change your perceptions, you can shape and direct your own genetic readout."

If this isn’t magical thinking, I don’t know what is.


In any case, Mercola seems to think that we can somehow magically change our DNA through epigenetic mechanisms just by thinking about it:

"So the good news is that you are in control of your genes … You can alter them on a regular basis, depending on the foods you eat, the air you breathe, and the thoughts you think. It’s your environment and lifestyle that dictates your tendency to express disease, and this new realization is set to make major waves in the future of disease prevention — including one day educating people on how to fight disease at the epigenetic level. When a disease occurs, the solution, according to epigenetic therapy, is simply to “remind” your affected cells (change its environmental instructions) of its healthy function, so they can go back to being normal cells instead of diseased cells."

And:

"You can also turn your genes off and on with your emotions too. Many, if not most people carry emotional scars; traumas that can adversely affect health. Using techniques like energy psychology, you can go in and correct the trauma and help regulate your genetic expression. My favorite technique for this is the Emotional Freedom Technique (EFT), but there are many others. Choose whichever one appeals to you, and if you don’t sense any benefits, try another, until you find what works best for you.

Please, remember that ‘You CAN Take Control of Your Health.’"

Mercola’s article is yet another supreme confirmation that magical thinking is at the heart of so much alternative medicine. No one argues that it’s not a good thing to improve one’s diet, to exercise, to avoid harmful substances. That’s a no-brainer, and science can give us the parameters for what is harmful and what is not. Even if it is true that emotions change gene expression through epigenetic mechanisms, it does not follow from that that we can actually control our gene expression in a way meaningful enough to make a difference in health. As someone once said about Deepak Chopra when he made similar claims, I’d like to see Mercola or Lipton alter their gene methylation just by thinking about it."

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"ἐδιζησάμην ἐμεωυτόν." [Heraclitus]

"All that exists is just and unjust and equally justified in both." [Aeschylus, Prometheus]

"The history of everyday is constituted by our habits. ... How have you lived today?" [N.]

*Become clean, my friends.*
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PostSubject: Re: EpiGenetics EpiGenetics EmptySat Jul 26, 2014 4:37 am

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PostSubject: Re: EpiGenetics EpiGenetics EmptyTue Apr 07, 2015 3:58 pm

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_________________
1. "Youth, oh, youth! | of whom then, youth, art thou born?
Say whose son thou art,
Who in Fafnir's blood | thy bright blade reddened,
And struck thy sword to my heart."


2. "The Noble Hart | my name, and I go
A motherless man abroad;
Father I had not, | as others have,
And lonely ever I live."
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Lyssa
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PostSubject: Re: EpiGenetics EpiGenetics EmptyThu Sep 03, 2015 6:24 am

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_________________
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"ἐδιζησάμην ἐμεωυτόν." [Heraclitus]

"All that exists is just and unjust and equally justified in both." [Aeschylus, Prometheus]

"The history of everyday is constituted by our habits. ... How have you lived today?" [N.]

*Become clean, my friends.*
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PostSubject: Re: EpiGenetics EpiGenetics EmptyFri Dec 04, 2015 11:07 am

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Fuck a nigger and get his brain cells, if it is a son.

_________________
1. "Youth, oh, youth! | of whom then, youth, art thou born?
Say whose son thou art,
Who in Fafnir's blood | thy bright blade reddened,
And struck thy sword to my heart."


2. "The Noble Hart | my name, and I go
A motherless man abroad;
Father I had not, | as others have,
And lonely ever I live."
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PostSubject: Re: EpiGenetics EpiGenetics EmptySun Mar 27, 2016 4:19 pm

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_________________
1. "Youth, oh, youth! | of whom then, youth, art thou born?
Say whose son thou art,
Who in Fafnir's blood | thy bright blade reddened,
And struck thy sword to my heart."


2. "The Noble Hart | my name, and I go
A motherless man abroad;
Father I had not, | as others have,
And lonely ever I live."
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OhFortunae

OhFortunae

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PostSubject: Re: EpiGenetics EpiGenetics EmptySat Dec 24, 2016 3:23 pm

Extremely interesting, linked to me by HyperKronos. [You must be registered and logged in to see this link.]

_________________
1. "Youth, oh, youth! | of whom then, youth, art thou born?
Say whose son thou art,
Who in Fafnir's blood | thy bright blade reddened,
And struck thy sword to my heart."


2. "The Noble Hart | my name, and I go
A motherless man abroad;
Father I had not, | as others have,
And lonely ever I live."
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